Association of insulin resistance and leptin receptor gene polymorphism in type 2 diabetes mellitus
نویسندگان
چکیده
منابع مشابه
Association of adiponectin gene rs2241766 polymorphism with serum adiponectin level, Insulin resistance and type 2 diabetes mellitus in an Iranian population
Introdution: Adiponectin is a peptide secreted from fat cells that plays an important role in the development of insulin resistance and type 2 diabetes. A number of single nucleotide polymorphisms in the adiponectin gene are associated with lower adiponectin expression and T2DM. The aim of this study was to determination the frequency of rs 2241766 polymorphism in adiponectin gene and its relat...
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Obesity and diabetes mellitus are two modern epidemics. But their interrelationship is debated. Here we explored the probable association among obesity, leptin and insulin resistance in type 2 diabetes mellitus. 60 recent onset (< 5 years) diabetics and age-sex matched 33 non diabetic controls were assessed for physical and chemical parameters like Body Mass Index, abdominal circumference, wais...
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Background: Patients with diabetes mellitus type II suffer from hyperglycemia because they are not able to use the insulin that they produce, often due to inadequate function of insulin receptors. There are some evidences that this deficiency is inherited in a dominant autosomal manner and leads to the malfunction of the pancreatic beta cells resulting in insulin excretion disorders. In this st...
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ژورنال
عنوان ژورنال: Journal of the Chinese Medical Association
سال: 2021
ISSN: 1726-4901
DOI: 10.1097/jcma.0000000000000507